![]() ![]() These children should be followed and cared for in a hospital with tertiary pediatric/cardiac intensive care units whenever possible. Some children clinically progress rapidly and may develop hemodynamic compromise. Any fever that is accompanied by symptoms concerning in their severity or coincident with recent exposure to a person with COVID-19 should raise suspicions. Persistent fever without a clear clinical source is the first clue. Any child with suspected MIS-C should also be evaluated for infectious and noninfectious etiologies. MIS-C is a rare complication temporally associated with COVID-19. When should you suspect MIS-C as part of your differential diagnosis? Elevated B-type natriuretic peptide (BNP) or NT-proBNP (pro-BNP), hyponatremia, elevated D-dimers.Lymphopenia An abnormal level of inflammatory markers in the blood, including elevated erythrocyte sedimentation rate (ESR)/CRP and ferritin, lactic acid dehydrogenase (LDH).Respiratory symptoms typically reported in adults with COVID-19 may or may not be present in pediatric patients with MIS-C.Ĭommon laboratory findings in case reports have included:.Shortness of breath suggestive of congestive heart failure or pulmonary embolism.Cytokine storm/macrophage activation or hyperinflammatory features.Toxic shock syndrome-like features with hemodynamic instability and poor heart function. ![]()
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